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During partial vagal blockade,in?ation produces a second inspiratory effort –Head’s paradoxical re?ex.

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The darkly stained tunica intima (TI) is delimited byan internal elastic membrane (IEM) that is easily distinguished even at thisrelatively low magnification.

However, a variety of hormones andhormonally active substances are not always discharged intothe bloodstream but are released into connective tissue spaces.They may act on adjacent cells or diffuse to nearby target cellsthat express specific receptors for that particular hormone(Fig.

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