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When most of thecells of the liver are involved, this is termed massive necrosis.As the name implies, this involves destruction of most or allof the hepatic acinus

When most of thecells of the liver are involved, this is termed massive necrosis.As the name implies, this involves destruction of most or allof the hepatic acinus. Gonococcal arthritis (disseminated gonococcal infection). This happens when lidocaineand prilocaine are mixed in equal proportion at25°C.

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For eachchemical of interest, one needs an analytical chemistry pro-tocol to measure concentration of the parent in the mediumbeing studied using liquid chromatography/mass spectrom-etry (LC/MS) or gas chromatography/mass spectrometry(GC/MS).

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